ncRNA name | Meg3 |
ncRNA Category | lncRNA |
ID | 17263 |
Ensembl | ENSMUSG00000021268 |
Synonyms | 2900016C05Rik, 3110050O07Rik, 6330408G06Rik, D12Bwg1266e, Gtl2 |
Disease name | retinal degeneration |
Species | Mus musculus |
Tissues/Cell_line | retinas |
Methods | TUNEL assay, Western blot, qRT-PCR |
Expression pattern | up-regulated |
Functional description | Light exposure leads to increased MEG3 expression.MEG3 silencing protects against light-induced retinal degeneration in vivo.MEG3 regulates photoreceptor cell apoptosis through p53- mediated transactivation |
PubMed ID | 29409883 |
Year | 2018 |
Title | Long non-coding RNA MEG3 silencing protects against light-induced retinal degeneration |
Drug-related ncRNA | NO |
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